NCLEX High-Yield Tips and Questions

COPD and Oxygen Therapy

Medical-Surgical · Respiratory / Pulmonology·Updated 2026-10-27

What it is

Chronic obstructive pulmonary disease (COPD) is persistent airflow limitation from chronic bronchitis and emphysema, most often caused by cigarette smoking. Loss of elastic recoil and narrowed airways trap air, so exhalation is the problem. In clients who retain carbon dioxide, high-flow oxygen worsens ventilation-perfusion mismatch and raises PaCO2, so oxygen is titrated to a target of 88% to 92%; it is never withheld from a hypoxemic client.

What the NCLEX focuses on

  • Findings: barrel chest, prolonged expiration, pursed-lip breathing, tripod position, accessory muscle use, diminished breath sounds, chronic productive cough.
  • Diagnosis: a post-bronchodilator FEV1/FVC ratio below 0.70.
  • Rising PaCO2 shows as drowsiness, headache and confusion; assess and obtain an ABG rather than assume the client is resting.
  • Exacerbation: increased dyspnea and sputum volume or purulence; treated with short-acting bronchodilators, systemic corticosteroids and antibiotics when sputum is purulent.
  • Noninvasive ventilation (BiPAP) is first-line for acute hypercapnic respiratory failure.
  • A Venturi mask delivers a precise oxygen concentration.
  • Small, frequent, high-calorie, high-protein meals offset the work of breathing.

Priority nursing actions

  1. Position the client upright, leaning forward on an overbed table.
  2. Assess respiratory rate, work of breathing, SpO2 and level of consciousness.
  3. Give oxygen titrated to SpO2 88% to 92% and obtain an ABG.
  4. Give prescribed bronchodilators and systemic corticosteroid.
  5. Prepare for noninvasive ventilation if PaCO2 rises with acidosis.
  6. Coach pursed-lip breathing.

Numbers to know

ValueNormal or targetWhy it matters
SpO2 target in COPD88% to 92%Corrects hypoxemia without raising PaCO2
pH7.35 to 7.45Below 7.35 with a high PaCO2 means respiratory acidosis
PaCO235 to 45 mm Hg (4.7 to 6.0 kPa)Above 45 mm Hg with acidosis supports NIV
FEV1/FVCBelow 0.70 after bronchodilatorConfirms airflow limitation
Long-term oxygen indicationPaO2 55 mm Hg or lower, or SpO2 88% or lowerImproves survival
Long-term oxygen useMore than 15 hours a daySurvival benefit

Common exam traps

  • Choosing to withhold oxygen from a hypoxemic client with COPD: wrong because hypoxemia kills faster than hypercapnia.
  • Choosing to raise oxygen until SpO2 reaches 100%: wrong because it raises PaCO2 and causes CO2 narcosis.
  • Choosing semi-Fowler position with arms at the sides: wrong because the tripod position lets the accessory muscles work.
  • Choosing to let assistive personnel decide the oxygen flow: wrong because that requires nursing judgment.
  • Choosing to treat new drowsiness as needed rest: wrong because it signals rising carbon dioxide.

What to teach

  • Pursed-lip breathing: inhale through the nose, exhale slowly through pursed lips about twice as long as inhalation.
  • Pace activities, rest before meals, and keep supplies within reach.
  • Home oxygen: no smoking and no open flames near oxygen; never change the flow without a prescription.
  • Stop smoking, get yearly influenza and recommended pneumococcal and RSV vaccines, and join pulmonary rehabilitation.

Client handout: Living With COPD (nurse guide and printable patient handout).

Try 2 NCLEX-style questions on this topic

From the NCLEXPace question bank. Pick your answers, then check them inside NCLEXPace.

Question 1 · QID B636F249

A client hospitalized for a COPD exacerbation becomes increasingly drowsy after the oxygen flow was increased. Which action should the nurse take first?

Select the best answer.

  1. A. Return the oxygen flow to the previous setting and then reassess the client's mental status
  2. B. Assess respiratory rate, effort, oxygen saturation, and level of consciousness immediately
  3. C. Ask the UAP to obtain a full set of vital signs while the nurse reviews the oxygen prescription
  4. D. Place the client in high-Fowler position and reassess alertness after several minutes
Question 2 · QID 39AC5406
For each finding, identify whether it indicates heart failure or chronic obstructive pulmonary disease (COPD).

For each finding, select Heart failure or COPD.

Heart failureCOPD
New S3 heart sound
Rapid weight gain and pitting edema
Pink, frothy sputum
Barrel-shaped chest
Prolonged expiration
Long history of productive cough
See the answers and full rationales

The correct answers, the reasoning for every option and 3,200+ more NCLEX questions are inside NCLEXPace. Create your account, then choose a plan to open them.

Create Account →

Read more on this topic

COPD vs Asthma on the NCLEX (and Why Oxygen Orders Differ)Respiratory Map: COPD, Asthma, Pneumonia, PE, and Chest TubesABG Interpretation in Four Steps (the ROME Method)

More tips on Medical-Surgical

Acute PancreatitisRecognize acute pancreatitis by pain and lipase, give fluids and pain control first, and catch hypocalcemia, shock and respiratory failure.Bowel Obstruction and NG Tube CareTell small from large bowel obstruction, spot strangulation early, and keep a decompression NG tube placed, patent and safe.Acute Kidney Injury vs Chronic Kidney DiseaseClassify AKI as prerenal, intrarenal or postrenal, follow its phases, and compare it with the staged, irreversible course of CKD.

Sources

  • Harding MM, Kwong J, Hagler D, Reinisch C. Lewis's Medical-Surgical Nursing: Assessment and Management of Clinical Problems. 12th ed. Elsevier; 2023; Chapter: Obstructive Pulmonary Diseases.
  • Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease: 2025 Report. GOLD; 2025.
Practice the NCLEX questions on this topic

3,200+ NCLEX questions with think-like-a-nurse rationales, unfolding case studies and adaptive readiness exams. Start with free practice questions, then choose a plan when you are ready.

Create Account →