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Chronic Disease Management: Hypertension, Diabetes, Hyperlipidaemia

Chronic Disease Management: Hypertension, Diabetes, Hyperlipidaemia

Written & reviewed by nurse educators·11 min read·Updated 2026-08-08
The short answer

Hypertension, diabetes and hyperlipidaemia travel together as metabolic syndrome and share one problem that shapes every exam question about them: they do not hurt, so adherence is the central nursing challenge. You want blood pressure, HbA1c, LDL and triglycerides down and HDL up, and because the conditions are silent the correct answer is often about adherence and follow-up rather than a symptom.

These three turn up together so often they have a collective name — metabolic syndrome. They also share a problem that shapes every exam question about them: they do not hurt. A client feels nothing while all three quietly damage arteries, which makes adherence the central nursing challenge rather than a side note.

The numbers, in one place

ConditionTargetDiagnostic threshold
Blood pressureGenerally under 130/80Elevated 120–129 systolic; stage 1 from 130/80; stage 2 from 140/90
HbA1cUsually under 7% (individualised)Diabetes at 6.5% or above; prediabetes 5.7–6.4%
Fasting glucose80–130 mg/dL before mealsDiabetes at 126 mg/dL or above
LDLUnder 100 mg/dL; under 70 if high cardiac riskOptimal under 100
HDLHigher is better — over 40 men, over 50 womenUnder 40 is a risk factor
TriglyceridesUnder 150 mg/dLOver 150 is raised

The one students invert: HDL is the good one and you want it high. H for Healthy, L for Lousy.

Hypertension

Called the silent killer because it has no symptoms until it has caused damage. When symptoms do appear — headache, visual changes, epistaxis — they signal severe elevation.

AspectWhat the nurse does
Measuring it properlySeated, feet flat, back supported, arm at heart level, correct cuff size, after 5 minutes of rest, no caffeine or smoking for 30 minutes. A cuff that is too small reads falsely high
Lifestyle firstDASH diet — fruit, vegetables, whole grains, low-fat dairy, reduced sodium. Weight loss, activity, limit alcohol, stop smoking
Common drugsThiazide diuretics, ACE inhibitors, ARBs, calcium channel blockers
The teaching that matters mostKeep taking it when you feel fine, and rise slowly — orthostatic hypotension is the commonest reason clients stop

Hypertensive crisis — over 180/120 with signs of organ damage such as headache, visual change, chest pain or confusion — is an emergency. Lower it gradually: dropping the pressure too fast causes stroke by under-perfusing a brain accustomed to high pressure.

Diabetes

Type 1Type 2
ProblemNo insulin producedInsulin resistance, later insufficient production
TreatmentInsulin alwaysLifestyle, oral agents, sometimes insulin
EmergencyDKA — ketones and acidosisHHS — very high glucose, no ketones

The rule of 15, for hypoglycaemia

Below 70 mg/dL in a client who can swallow: give 15 g of fast-acting carbohydrate — 4 oz juice, 3–4 glucose tablets, 1 tbsp honey — wait 15 minutes, recheck. Repeat up to three times, then follow with a protein-containing snack once above 70. If the client cannot swallow: glucagon IM or subcutaneous, or IV dextrose.

Signs to recognise: cold, clammy, shaky, tachycardic, confused, irritable. The memory hook is cold and clammy, need some candy — against hyperglycaemia's hot, dry and drowsy. Note that beta blockers mask the tachycardia and tremor, so a client on one may only sweat.

Sick-day rules

Illness raises glucose even when a client is not eating, and this is a common exam item:

  • Never stop insulin because of not eating. Illness increases the requirement.
  • Check glucose every 2 to 4 hours, and ketones if type 1.
  • Keep drinking — sugar-free fluids if glucose is high, carbohydrate-containing if low.
  • Call the provider for glucose persistently over 240, ketones, vomiting, or inability to keep fluids down.

Insulin and foot care

Regular insulin is the only insulin given IV. When mixing regular with NPH, draw up clear before cloudy — regular first. Rotate sites within one region; the abdomen absorbs fastest.

Foot teaching, which appears constantly: inspect daily including between the toes and with a mirror if needed, wash in warm not hot water, dry thoroughly, never go barefoot, never use heating pads or cut corns, cut nails straight across, and see a podiatrist. Neuropathy means an injury can go unnoticed until it is infected.

Hyperlipidaemia

AspectDetail
StatinsFirst-line. Report muscle pain or weakness — rhabdomyolysis. Monitor liver enzymes. Avoid grapefruit juice
TimingOlder statins are taken in the evening because cholesterol is synthesised overnight; newer long-acting ones can be taken any time
Fibrates and niacinMainly for triglycerides. Niacin causes flushing — aspirin beforehand helps, and it is expected rather than allergic
Bile acid sequestrantsInterfere with absorption of other drugs and fat-soluble vitamins; separate doses
DietReduce saturated and trans fat, increase soluble fibre and oily fish. Mediterranean pattern

A statin is often started after a cardiac event regardless of the cholesterol number, because the benefit is not only lipid lowering. Clients ask why they need it when their cholesterol is normal — that is the answer.

What they share, and what the exam does with it

Shared featureNursing consequence
All three are asymptomaticAdherence is the main intervention. Explore barriers — cost, side effects, forgetting, not believing it matters
All three damage the same vesselsThey multiply cardiovascular risk together rather than adding to it
All three improve with the same lifestyle changesOne conversation about diet, activity and smoking serves all three
All three need regular follow-upA missed appointment is a clinical problem, not an administrative one

When a question asks for the priority teaching for a client with all three, look for the option addressing something shared — smoking cessation, or taking medication as prescribed — rather than one disease-specific detail.

NCLEX tip: These conditions are silent, so the correct answer is often about adherence and follow-up rather than a symptom. And remember the direction of each target: you want blood pressure, A1c, LDL and triglycerides down, and HDL up. HDL is the one that goes the other way, and it is the one students get wrong.

Frequently asked questions

Common follow-up questions on Body Systems & Clinical Content.

Which cholesterol number do you want high?

HDL is the good one and you want it high, over 40 in men and over 50 in women, with under 40 a risk factor. The memory hook is H for Healthy, L for Lousy. LDL, by contrast, you want under 100 mg/dL, or under 70 if cardiac risk is high.

What is the rule of 15 for hypoglycaemia?

For a client below 70 mg/dL who can swallow, give 15 g of fast-acting carbohydrate such as 4 oz juice, 3 to 4 glucose tablets or 1 tbsp honey, wait 15 minutes, and recheck, repeating up to three times, then follow with a protein-containing snack once above 70. If the client cannot swallow, give glucagon IM or subcutaneous, or IV dextrose. Note that beta blockers mask the tachycardia and tremor, so a client on one may only sweat.

What are the diabetic sick-day rules?

Never stop insulin because of not eating, since illness increases the requirement. Check glucose every 2 to 4 hours, and ketones if type 1, and keep drinking, using sugar-free fluids if glucose is high and carbohydrate-containing fluids if low. Call the provider for glucose persistently over 240, ketones, vomiting, or an inability to keep fluids down.

Why is a statin started even when cholesterol is normal?

A statin is often started after a cardiac event regardless of the cholesterol number, because the benefit is not only lipid lowering. Clients frequently ask why they need it when their cholesterol is normal, and that is the answer. Statins are first-line, and clients should report muscle pain or weakness because of the risk of rhabdomyolysis.

How should a hypertensive crisis be managed?

A hypertensive crisis is over 180/120 with signs of organ damage such as headache, visual change, chest pain or confusion, and it is an emergency. Lower the pressure gradually, because dropping it too fast causes stroke by under-perfusing a brain accustomed to high pressure. This reflects the same adherence-and-follow-up focus these silent conditions demand.

Put this into practice

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